Extensive Resection of Small Intestine

Deficiency of vitamin B12 after extensive resection of the distal small intestine in an infant.

Man may survive resection of surprisingly large amounts of the small intestine. As little as 7 in. of jejunum and ileum may be sufficient to support life, atleast for a time (Jackson, Linder and Berman, 1951), and a large number of patients have survived less extensive resections and have remained well (Flint, 1912; Haymond, 1935; West, Montague and Judy, 1938; Althausen, Uyeyama and Simpson, 1...

Early Adaptation of Small Intestine After Massive Small Bowel Resection in Rats

BACKGROUND It is important that the residual bowel adapts after massive resection. The necessary intestinal adaptation is a progressive recovery from intestinal failure through increase in absorptive surface area and functional capacity and includes both morphological and functional adaptations. OBJECTIVES The aim of this study was to investigate intestinal morphological and functional adapta...

Histomorphometric changes of small intestine in pregnant rat

Food intake of rats increases during pregnancy. This requires changes in the structure of the small intestine to absorb additional food. The aim of the present study was to investigate the morphological changes in the layers of small intestine in rats during pregnancy. Duodenum, jejunum and ileum of 18 pregnant Sprague-Dawley rats (day 7, 14 and 21 of pregnancy) were collected. Villous height a...

Tissue-engineered small intestine improves recovery after massive small bowel resection.

OBJECTIVE Rescue with tissue-engineered small intestine (TESI) after massive small bowel resection (MSBR). SUMMARY BACKGROUND DATA Short bowel syndrome is a morbid product of massive small bowel resection. We report the first replacement of a vital organ by tissue engineering with TESI after MSBR. METHODS Ten male Lewis rats underwent TESI implantation with green fluorescent protein (GFP)-m...

Duplication of small intestine.